Prioritizing Rare Variants with Conditional Likelihood Ratios
نویسندگان
چکیده
منابع مشابه
Prioritizing rare variants with conditional likelihood ratios.
BACKGROUND Prioritizing individual rare variants within associated genes or regions often consists of an ad hoc combination of statistical and biological considerations. From the statistical perspective, rare variants are often ranked using Fisher's exact p values, which can lead to different rankings of the same set of variants depending on whether 1- or 2-sided p values are used. RESULTS We...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2015
ISSN: 0001-5652,1423-0062
DOI: 10.1159/000371579